Yanbo Xu
Alind Khare
Glenn Matlin
Monish Ramadoss
Rishikesan Kamaleswaran
Chao Zhang
Alexey Tumanov
October 19, 2022
Publication
A cost-aware and uncertainty-based framework for dynamic 2D prediction in multi-stage classification systems.
Published
October 19, 2022
Authors
Yanbo Xu, Alind Khare, Glenn Matlin, Monish Ramadoss, Rishikesan Kamaleswaran, Chao Zhang, Alexey Tumanov
Venue
Neural Information Processing Systems (NeurIPS) 2022

Machine Learning (ML) research has focused on maximizing the accuracy of predictive tasks. ML models, however, are increasingly more complex, resource intensive, and costlier to deploy in resource-constrained environments. These issues are exacerbated for prediction tasks with sequential classification on progressively transitioned stages with “happens-before” relation between them.
We argue that it is possible to “unfold” a monolithic single multi-class classifier, typically trained for all stages using all data, into a series of single-stage classifiers. Each single-stage classifier can be cascaded gradually from cheaper to more expensive binary classifiers that are trained using only the necessary data modalities or features required for that stage.
UnfoldML is a cost-aware and uncertainty-based dynamic 2D prediction pipeline for multi-stage classification that enables:
UnfoldML achieves within 0.1% accuracy of the highest-performing multi-class baseline in clinical settings, while saving close to 20× on spatio-temporal inference cost and predicting disease onset 3.5 hours earlier. The framework also generalizes to image classification, saving close to 5× cost with as little as 0.4% accuracy reduction.
@inproceedings{xu2022unfoldml,
title = {UnfoldML: Cost-Aware and Uncertainty-Based Dynamic 2D Prediction for Multi-Stage Classification},
author = {Xu, Yanbo and Khare, Alind and Matlin, Glenn and Ramadoss, Monish and Kamaleswaran, Rishikesan and Zhang, Chao and Tumanov, Alexey},
booktitle = {Advances in Neural Information Processing Systems 35 (NeurIPS 2022)},
pages = {4598--4611},
year = {2022}
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